Biography:

Dirk Kuckling has completed his PhD from the CAU Kiel, Germany. He further performed research at TU Dresden, Germany and Stanford University, USA. Since 2008 he is full professor for Organic and Macromolecular Chemistry at the University of Paderborn, Germany. He has published more than 130 papers in reputed journals and has been serving as an editorial board member of repute.       

Abstract:

Vegetable oils are biorenewable triglycerides of fatty acid extracted from plants. The utilization of vegetable oils as renewable resource in polymeric material application has attracted significantly increasing attention due to their renewability, low cost, low toxicity, inherent biodegradability and versatile functionality. The fatty acid composition of different vegetable oils depends on the plant and growing conditions. However, in the unsaturated structure the first double bond is invariable located between 8^th and 9^th carbon, which is independent of the fatty acid type.[1] There are several methods to convert the unsaturated fatty acid to functionalized monomers. Utilization of ozonation technology for double bound cleavage followed by reductive or oxidative workup can give A₃ monomers with defined structures.[2] In this work, trialcohol, trialdehyde and triacid were synthesized by employing ozonolysis of castor oil and soybean oil. Using these A₃ monomers, a variety of hyperbranched polymers, such as hyperbranched polyester (HBPE), hyperbranched polycarbonate (HBPC), hyperbranched polyacetal (HBPA) etc., were successfully prepared by A₃+B₂ condensation polymerization. The resulting hyperbranched polymers were characterized by NMR spectroscopy for endgroup analysis, size exclusion chromatography (SEC) for molar masses and differential scanning calorimetry (DSC) for thermal properties.

Biography:

Keisham Surjit Singh has completed his PhD from North Eastern Hill University, Shillong, India and then joined as Lecturer in the Department of Chemistry, NERIST, Arunachal Pradesh, India. In 2010, he joined as Assistant Professor in National Institute of Technology, Agartala, India. He has published more than 20 papers in reputed journals like New Journal of Chemistry, Inorganica Chimica Acta, Journal of Organometallic Chemistry, etc. He acts as reviewer for Medicial Chemistry Research, Complex Metals, etc., and has been serving as an Editorial Board Member of International Journal of Scientific and Engineering Research.

Abstract:

Triorganotin(IV) complexes of azo-carboxylic acids were synthesized by the reaction of 2/4-(2,4-dihydroxy-phenylazo)-benzoic acids with appropriate triorganotin(IV) chlorides [R= Me for compounds  Me₃SnH₂L¹ and Me₃SnH₂L²;  Ph for compounds  Ph₃SnH₂L¹ and Ph₃SnH₂L² and Bu for compound Bu₃SnH₂L²] in presence of triethylamine. The characterization of the complexes was accomplished by elemental analyses, UV, IR and multinuclear (¹H, ¹³C and ¹¹⁹Sn) NMR spectroscopy. Structure of Me₃SnH₂L² was established by X-ray crystal structure analysis. X-ray crystal structure of Me₃SnH₂L² revealed that the compound exhibits a 48 membered macrocyclic-tetrameric structure with trigonal bipyramidal geometry around the tin atoms in which the three methyl groups occupy the equatorial positions while the apical positions are being occupied by the oxygen atom of carboxylate group of one ligand and the phenoxide oxygen atom of another ligand. All the complexes display a sharp singlet ¹¹⁹Sn resonance in the range specified for the four coordinate structures suggesting that complexes havee tetrahdral structures in solution. The five coordinate structure of the complexes in solid state dissociated into monomeric species with four coordinate structures in solution. Anti-diabetic activities of the complexes were studied and the results showed that the synthesized compounds exhibited effective activity even higher than the standard compound acarbose.

Biography:

Ukiwe Lugard Luke Nnabugwu is a Senior Lecturer in the Dept. of Chemistry, Federal University of Technology, Owerri, Nigeria. He specialized in Environmental Chemistry, with bias in Environmental Pollution and Control. He has authored and co-authored more than 65 publications in reputable journals and has served as Reviewer to a number of journals.

Abstract:

The present research investigated the synthesis of a novel adsorbent by combining Moringa oleifera and silver nitrate (AgNO₃). The chemical components of the pre-adsorbent and adsorbent material were characterized using Fourier Transform infrared Spectroscopy (FTIR), while the equilibrium adsorption capacity (Qe) obtained for Copper (Cu), Manganese (Mn) and iron (Fe) were 0.042, 0.039 and 0.041 respectively. These results indicated that the adsorbent was able to remove Mn more than Cu and Fe from the aqueous salt mixture. However, the results observed for the biofilm experiment revealed that the M. oleifera-AgNO₃ biocidal action was effective in deactivating oxidizable components in the wastewater system after 8 days. The above findings have demonstrated that the synthesized M. oleifera-AgNO₃ adsorbent would be effective in cleaning-up waste streams contaminated with microbes and trace metals.

Biography:

Abdelnasser Mabrouk works as a Scientist at Water Desalination department, Qatar Environment & Energy Research Institute, Qatar. He is a specialist in the process design and techno-economics of thermal water desalination process. He has an industrial experience in desalination plant process design. He led several R&D projects during his work in Doosan Heavy Industries, Desalination R&D Center (UAE) to improve the thermal/membrane desalination technology (MSF, MED, RO, NF and FO) for market competence. He published several publications (30 papers) in reputed journals and also presented his research work in international conferences (24 papers). He published a book and 3 book chapters. He has 4 US provisional patents, GCC patent and 5 IP disclosures in the desalination process development.

Abstract:

This work presents a novel tube bundle arrangement of MED evaporator.  The tube bundle is arranged to allow the generated vapor to flow in a smooth path and minimized route to reach the next effect. This route is designed in order to avoid shear loss to avoid breakdown of film liquid around tubes (dry zones) as a result not abruption the heat transfer process. Also this route will eliminate the vapor entrainment which reduce the brine carry over since there is no cross flow; consequently, there is no need for the demister. Also, the novel route is target to eliminate vapor boxes and directed the generated vapor in the current effect to the next effect through holes in the tube sheet. Also the holes of the tube sheets make sure the vapor is uniform distribution before the entrance to the next tubes bundle which eliminates the entrance loss. Process design calculations using VSP software showed that, for the same gain output ratio (GOR=9), the required heat transfer area of novel evaporator is 22% lower than that of existing evaporator.  This is due thermal losses reduction (demister loss and vapor box loss) in the novel MED evaporator. The thermal loss reduction in the novel evaporator varies from 20% to 50%.  Due to removal of demister in the novel MED evaporator, the evaporator width decreases by 65% however the novel evaporator height is almost double of the existing evaporator. The novel evaporator length is 6% lower than the existing evaporator. Due to reduction in the novel evaporator width and length, the foot print decreases by 65% lower than the existing evaporator. The cost of tubes of the novel evaporator is 18% lower than the traditional MED. This is mainly due to reduction in heat transfer area as a result of improvement of heat transfer process.  Also, the shell material of the novel evaporator is 24% lower than that of the traditional MED-TVC. This is due to significant reduction in the evaporator width as a result of removing demister. The new design will minimize the thermal losses inside evaporator which will reduce the required heat transfer area and get a compact evaporator size. The expected reduction in heat transfer area not only reduces the capital cost of evaporator manufacturing but also will reduce the foot print of the MED desalination plant significantly.

Biography:

Jane Catherine Ngila has a Bed (Sci) and MSc (Chemistry) from Kenyatta University (KU), Kenya (1986 and 1992) and PhD from UNSW Australia (1996). She worked as a tutorial fellow/Lecturer at KU from 1989-1997 and as a Lecturer/Senior Lecturer from 1998-2006 at University of Botswana. She also worked as Senior Lecturer from 2006-2011 at University of KwaZulu Natal and as Professor of Chemistry at University of Johannesburg (UJ) in April 2011. She has taught various courses in Analytical/Environmental Chemistry and research in water quality monitoring and treatment using nanocomposite membranes; modelling mass balance in wastewater treatment plants. She has published more than 100 journal articles and graduated more than 50 postgraduate students.

Abstract:

We report dechlorination of mixed pesticides (dieldrin, chlorpyrifos, diuron and fipronil) using Fe-Pd nanoparticles anchored on acrylic acid (AA) grafted mesoporous silica (MS) membrane as inert support designated as (Fe-Pd/MS-g-PAA). Nanocomposites made up of inorganic nanoparticles give enhanced performance due to their high surface area to volume ratio. When Fe-Pd is loaded on MS-g-PAA substrate, the costly post-treatment and filtration processes associated with powdered materials are eliminated. Chlorinated pesticides are manufactured in large quantities primarily for eradication of pests in agriculture. However, they finally end up in our soils, food and water sources. These pesticides are cholinesterase inhibitors and their adverse health effects manifest in the nervous, immune and endocrine systems. Therefore, their removal from contaminated water is necessary. Bimetallic iron-palladium nanoparticles immobilized on MS-g-PAA were used for their dechlorination to benign products. The loading of Fe-Pd was done by adding 1 g MS-g-PAA to a ferrous sulfate solution followed by reduction with NaBH_4. The precipitate was then added to palladium acetate solution, reduced, filtered, washed and dried. The composite was characterized using FTIR, XRD, SEM, BET and TEM and chemical analysis was done using GCxGC-TOFMS. The results obtained show that 95 to 99% of dieldrin, chlorpyrifos and diuron were dechlorinated in 60, 120 and 180 minutes respectively, while for fipronil, it took 180 minutes to reach 90%. The data was processed to obtain kinetic parameters. However, mineralization rate (m_r) was low at 36%, 45%, 43% and 45% for chlorpyrifos and dieldin, fipronil and diuron, respectively.

Biography:

Aleksandr Ketov completed PhD and is a Professor in Inorganic Materials research and Chemical Engineering. With over 25 years of professional experience in material research and inorganic chemistry, he is a Candidate of Science degree (corresponding to PhD) from the Institute of Technology (St-Peterburg) and has obtained the full Doctor and Professor Positions from the Perm State Technical University. He has more than 30 patents of Russia and more than hundred other written works.

Abstract:

Porous glasses with closed cell structure and densities lower than 250–300 kg m^–3 are rather attractive as functional heat-insulating materials. It was found the possibility of obtaining low-density cellular silicate materials by the hydrate mechanism due to the stronger gas evolution in the course of the redox reaction between water vapor and carbon. The research results were obtained by synchronous thermogravimetric and MS analysis, SEM, X-ray phase analysis. It was found that raising the number of Na⁺ ions in the raw silicate formulation leads to an increase in the amount of bound water removed at thermal plasticity temperatures of sodium-calcium glasses (973–1073 K). The redox reactions between steam and carbon in synthesis of a cellular silicate material favor an increase in the gas evolution and a decrease in the density of the material obtained. Synthesis of glass from hydrated polysilicates in the intergrain space of dispersed glass can be used to obtain foamed-glass materials and secondary use of a low-grade sodium-calcium glass. The presented method of obtaining cellular material can use any glass wastes as a raw without extra cooking and to obtain the material similar to the commercial foamed glass of blocked and granulated types. The use of non-powder preforms enables applying efficient technological methods in production and obtaining products with new properties such as large-size items, colored ones or those acceptable for facing and also light-weight construction mixes. The applications of obtained materials are presented and discussed.

Biography:

O Tafat-Igoudjilenê is a Professor in Chemistry at the University of Science and Technology Houari Boumedienne, Àlgeria. She has published l0 papers in reputed journals (in Thermodynamic) and has participated in several international conferences in Chemistry.

Abstract:

The purpose of this work was to determine the vapor-liquid equilibrium, of heptan-2-one+1,4-dichlorobutane or l,6-dichlorohexane with view to study the effect of specific interaction (carbonyl-chlorogroup) on the excess Gibbs energies of heptan-2-one+halogenated hydrocarbons. Halogenated hydrocarbons are manufactured in large quantities and have many applications (as refrigerant, organics solvents and medicines). The vapor pressure of the pure compounds and the binary mixtures were measured by means of a static apparatus at temperatures between (263.15 and 343.15) K. The apparatus allows measurements in the P ranging from 27 to 200 10³ Pa and from 258 to 468 K .Vapor pressure was measured by means of pressure gauges (Rosemount, model 1151 DPE 22S2, Minneapolis, Minn, USA), protected by a differential (pressure indicator MKS, Mode1615D, MKS Instruments, USA). The experimental data of excess molar Gibbs energies, G^E, have been compared with values using the DISQUAC group contribution model.

Biography:

Akira Katayama is a PhD course student from H Masuda’s group of Nagoya Institute of Technology and is a JSPS Research fellow (DC2). He received Master of Engineering and Bachelor of Engineering from the same institute.

Abstract:

An ionic liquid, which is a salt in a liquid state under ambient conditions, has recently been employed in a number of different research fields, because it has several unique properties such as low volatility, large electrochemical window, high thermal and chemical stabilities, and high electric conductivity. The reduction of small molecule, such as CO_2, O₂, in ionic liquid has been researched because the reactivity is different from that in conventional organic solvents. On the other hand, the reduction of N₂ in ionic liquid has never been reported. We have reported the first example of the electrochemical reduction of N₂ to NH₃ using the W E coated with Cp₂TiCl₂–supported ionic liquid under ambient conditions.  In this study, we used the ionic liquid, 1−butyl−1−methylpyrrolidinium tris (pentafluoroethyl) trifluoro−phosphate ([C₉H₂₀N]⁺[(C₂F₅)₃PF₃]^–), which is appropriate for use as a supporting material, because of its high chemical stability. When the controlled potential electrolysis was carried out at -1.5 V (vs. Ag/AgCl), the yield of NH₃ per Cp₂TiCl₂ and current efficiency were 27% and 0.2%, respectively, which are significantly higher in comparison with those reported previously. In this paper, we will report the controlled potential electrolysis by Cp₂TiCl₂^- supported [C₉H₂₀N]⁺ [(C₂F₅)₃PF₃]^– under other experimental conditions.

Biography:

Pawanpreet Kaur is pursuing PhD under the supervision of Dr. Raghubir Singh in Department of Chemistry, DAV College, India. Her area of research is “Monitoring of metallic toxins using azomethinic cyclic and semi-cyclic receptors”.

Abstract:

An “off-on-off” type tripodal Schiff base chemosensor derived from condensation of tris(2-aminoethyl)amine and 2-hydroxynaphthalene-1-carboxaldehyde exhibiting pronounced fluorescence signaling for Zn²⁺ and Cd²⁺ as well as chromogenic response towards Fe³⁺, Fe²⁺, Zn²⁺ and Cd²⁺ ions has been explored herein. The sensor can be considered as molecular switch which turns “ON” upon selective binding with Zn²⁺/Cd²⁺ ions and “OFF” in the simultaneous presence of Zn²⁺/Cd²⁺ and IO₄^- ion. The addition of metallic cations induces a remarkable colorimetric response from yellow to colorless (for Zn²⁺, Cd²⁺), purple (for Fe³⁺) and light green (for Fe²⁺). Therefore, the sensor can easily differentiate two states of iron (Fe³⁺ from Fe²⁺) by revealing distinctive colors. In addition, the detection limit of the sensor towards Zn²⁺/Cd²⁺ was slowed down to nanomolar concentration. Thus, it is potentially significant sensor and can be applied to both the environment and biological systems.

Biography:

Zaw Ye Maw Oo has completed his PhD from D. Mendeleev University of Chemical Technology of Russia. Currently, he is attending Post-doctoral studies in that university. He has published more than 5 papers in reputed journals.

Abstract:

Porous materials are commonly used as catalyst supports in the processes of oxidation, hydrogenation and dehydrogenation at high temperature, corrosion in feed processing - corrosive environments at endothermic and exothermic reactions in particular, for this purpose, various types of corundum materials with high chemical inertness. Porosity materials due to the high porosity and the peculiar structure have specific properties dramatically different from those of the corresponding chemical composition of dense materials. There was obtained a highly porous cellular material of alumina carriers for catalysts. The filler used to be electro corundum, as reinforcing filler, forming on fire a bundle used porcelain. The samples were prepared by impregnating the ceramic slurry polyurethane foam (PUF), followed by drying and calcining at 1450°C. The porosity after firing was 60-65 %, the compressive strength of 3.5 MPa.

Biography:

Jaswant Singh is currently pursuing PhD under the supervision of Dr. Varinder Kaur and Dr. Raghubir Singh in Department of Chemistry, Panjab University, India. He is potentially working on “Synthesis and characterization of Macrocyclic molecules and their interactions with neuro-toxins”

Abstract:

1-(2-hydroxyphenyl) ethanone synthesized by the condensation of 2-hydroxyacetophenone and ethanolamine has been known as potential ligating molecules for coordinating copper. Herein, it is explored as a receptor to study its optical behavior towards some metallic species via naked eye chemo-sensing, UV-Visible spectrometry and Fluorescence studies using water -methanol (80:20) mixed solvent system. Interestingly, the receptor behaved as a colorimetric switch selectively for Fe (III) species and fluorphore for Zn (II) and Cd (II) species. The optical behavior of receptor molecule (5×10^-4 M) towards Fe³⁺ was in the range 0.05-0.85 mM in water-methanol mixture, which showed a color switch from yellow to red with the appearance of corresponding absorbance bands centered at 329 and 387 nm. Furthermore, receptor molecule “turned on” the fluorescence at excitation of 380 nm with respective emission bands at 451 nm and 448 nm for Zn and Cd. Moreover, the strategies were optimized to determine these metal ions in pharmaceutical samples and environmental natural samples.

Biography:

Petr Ketov has completed graduation from Dmitry Mendeleev University of Chemical Technology of Russia in 2011 and is a Post-graduate student of Perm State Technical University. He has 4 patents of Russia and more than 7 articles in reputed journals. He has about 10 years of professional experience in material research and inorganic chemistry.

Abstract:

Nanocarbon fibers produced by catalytic dehydrogenation of hydrocarbons are considered to be a promising material for solving problems of sorption, catalysis, and construction materials science. However, their synthesis comes across a number of technological and materials science related problems. Method of catalytic dehydrogenation of hydrocarbons to obtain nanocarbon fibers directly on the surface of an inert macroporous support is considered. The specific features and limitations of the method are discussed. It was demonstrated that the method of homogeneous deposition of Ni²⁺ compounds onto the surface of coarsely porous supports enables a uniform distribution of Ni²⁺compounds over the support surface in a dispersity acceptable for further catalytic pyrolysis of hydrocarbons on a material of this kind for obtaining coatings composed of nanocarbon fibers. It was shown that the distribution of Ni²⁺ among the solution, precipitate, and amount deposited onto the support surface in the course of homogeneous deposition in the reaction of carbamide hydrolysis in the presence of soluble Ni²⁺ salts is of a rather complex nature, being determined primarily by temperature, time, Ni²⁺ and (NH₂)₂CO concentrations, and S/V ratio of a support placed in solution. The fraction of Ni²⁺ that is deposited on the support surface and cannot be involved in the pyrolysis process was determined. Every mole of nickel satisfying the hydrocarbon pyrolysis conditions can produce 4230±150 g of carbon as a result of the catalytic pyrolysis of butane.

Biography:

Hüseyin Özkan Toplan has completed his PhD in 1998 from Sakarya University. He has been working at the Sakarya University, Metallurgy & Materials Engineering, as an academic staff since 1990. He has attended more than 35 national and international conferences. He has published more than 30 papers in reputed journals and his publications have been cited more than 150.

Abstract:

The MgO-Al₂O₃-SiO₂-TiO₂ glass system was prepared by melting method. The crystallization behavior and crystallization kinetics of a sample with glass ceramic composition were examined. DTA and XRD analysis revealed the crystallization of Ca_0.965Mg₂Al₁₆O₂₇ cordierite (Mg₂Al₄Si₅O₁₈) and Fe₂TiO₅ phases. The activation energy for the crystallization of cordierite phase has been evaluated, and the crystallization mechanism has been studied by applying DTA measurements performed at various heating rates. The results indicate that the dominant crystallization mechanism for this system is bulk crystallization dominated by three-dimensional growth. The average calculated values of crystallization and viscous flow for the formation of crystal phases from the glass matrix were measured to be 330 kJmol^-1 and 377 kJmol^-1, respectively.

Biography:

L I Velikanova has completed his PhD and Post-doctoral studies from NWSMU n.a. I I Mechnikov Saint-Petersburg, Russia. He is the Director of research laboratory of chromatography at NWSMU n.a. I I Mechnikov Saint-Petersburg. He has published more than 30 papers in reputed journals and is a researcher interested in the use of chromatography in endocrinology.

Abstract:

We developed the technique of the urinary steroid profiles (USP) generation by gas chromatography–mass spectrometry (GC-MS) and optimized sample preparation procedure and conditions of chromatographic analysis. The enzyme for hydrolysis (64 h, t 37⁰С) was sulfatase from Helix pomatia. Steroids were extracted with chloroform. The efficacy of derivation was increased by enlargement of methoxyamine solution volume in pyridine to 160μL and ТSIM to 500μL for 5ml of urine. 5α-androstanediol was an internal standard for quantitative calculations. 66 steroids by a GC–MS QP2010 ULTRA gas chromatograph–mass spectrometer (Shimadzu, Japan) were determined. 4 types of USP for 32 patients with adrenocortical carcinoma (ACC) are revealed by GC-MS. The difference between them was androgen and glucocorticoid secretion. 15 main ACC features were observed by GC-MS. 100% sensitivity and specificity of ACC and adrenocortical adenoma (ACA) differential diagnosis were achieved by combination of following parameters: THS> 900 µg/24 h and/or DHEA> 1500 µg/24 h with ratios of 3α,16,20-pregnentriol/ 3β,16,20-pregnentriol (3α,16,20dP3 /3β,16,20dP3) less than 6.0 and 3α,17,20dP3 /3β,17,20dP3 less than 9.0 and the detection of non-classical 5-en-pregnens, not found in ACA and healthy persons. Features of 21-hydroxylase and 11β-hydroxylase deficiency were found in 32.2% and in 61.3% patients with ACC respectively. The decrease of activity of 21-hydroxylase in patients with ACA was also found. Probably, it is found one of the pathogenetic mechanisms in the formation of adrenal cortex tumor and malignance.

Biography:

Mustafa Kucukislamoglu has completed his PhD from Karadeniz Technical University. He has been working at the Sakarya University, Chemistry Department as an academic staff since 1999. He has attended more than 30 national and international conferences. He has published more than 40 papers in reputed journals and his publications have been cited more than 350.

Abstract:

The synthesis, reactions and biological properties of substituted coumarins constitute a significant part of modern heterocyclic chemistry. Compounds containing a coumarin moiety display a broad spectrum of biological activities such as antimicrobial, antifungal, anticoagulant, anti-HIV and insecticidal properties. Coumarins are an important class of CAIs for several reasons: (i) they were the first CAIs showing a high selectivity for inhibiting CA isoforms of interest for pharmacologic applications, such as the tumor-associated ones (hCA IX and XII, which are targets for antitumor/ anti-metastatic drugs) or the mitochondrial ones (CA VA and VB, which are targets for anti-obesity agents). 20 thiourea bearing coumaryl-3-carboxamid compounds were synthesized for the investigation of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activities.

Biography:

Mustafa Arslan has completed his PhD from Cleveland State University. He has been working at the Sakarya University, Chemistry Department as an academic staff since 1998. He has attended more than 35 national and international conferences. He has published more than 40 papers in reputed journals and his publications have been cited more than 400.

Abstract:

Heterocyclic moieties, such as indoles, thiazolidine-4-ones, pyrazoles, piperazines, pyridines, etc., always have considerable attention due to their pharmacological activities. Heterocycles bearing one or more nitrogen and sulfur atoms have received more attention recently. Among the most frequently encountered heterocyclic compounds, thiazole and its derivatives play an important role in nature. The heterocyclic compounds have broad applications including the treatment of hypertension, bacterial and HIV infections, allergies and as antibiotics and ligands for estrogen receptors.  Besides, these compounds have used as inhibitors against fructose 1, 6-bisphosphatase, tumor associated carbonic anhydrase isoforms hCA IX and hCA XII, sphingosine kinase and evaluation of in vitro anticancer activity. 12 sulfonamide bearing thiazole compounds were synthesized for the investigation of carbonic anhydrase enzyme activity.

Biography:

Mustafa Zengin has completed his PhD from Sakarya University. He has been working at same University in the Chemistry Department as an academic staff since 1998. He has attended more than 35 national and international conferences. He has published more than 20 papers in reputed journals and his publications have been cited more than 200.

Abstract:

Nitrogen-containing five-membered heterocyclic compounds are found in the structures of several natural products and pharmaceuticals. Most of them are used as synthetic intermediate products, reactants, ligands or asymmetric synthesis catalysts. Because their many synthesized derivatives are biologically active, thiazolidine has recently become an increasingly used heterocyclic system. We synthesized TCA derivatives and investigated their antibacterial properties on multi-drug resistant (MDR) bacteria. The result showed that TCAs have significant antibacterial activity on Gram-positive (S. aureus) and Gram-negative bacteria (Pseudomanas, Acinetobacter and Escherichia coli).

TCA derivatives are structural analogue of proline. Therefore, it can inhibit bacterial growth by mimicking various essential functions of naturally occurring amino acids. The molecules have been synthesized for antibacterial studies at a high yield using cheap and easily accessible starting materials.